Science Cafe presents
Martin Holcik, Professor and Chair, Department of Health Sciences
Lost in translation: linking protein synthesis to human disease
Translation, or protein synthesis, is an essential mechanism required to decode cellular information stored in nucleic acids into proteins, the building blocks of cells. It is now well established that cellular stress, both physiologic and pathophysiologic, selectively modulates protein synthesis in order to match the correct protein output to the conditions. The mechanisms allowing this selective control, and their links to human disorders will be presented and discussed.